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ICD Code: 765.1 Other preterm infants; preterm delivery; low birth weight (LBW) (1000 to 2499 grams and/or a gestation less than 28 to 37 weeks)



ICD Code: 765.1 Article Review
Title: Brooks A-M et al; "Impact of Low Birth Weight on Early Childhood Asthma in the United States." Archives of Pediatrics and Adolescent Medicine; V.155; 3/01; p401
      STUDY DESIGN: The authors used a nationally representative sample to estimate the strength of the association between low birth weight (LBW) and asthma (relative risk) as well s the magnitude of population-wide impact of LBW on the number of children with asthma (attributable risk). Data from the 1988 National Maternal-Infant Health Survey and the 1991 Longitudinal Follow-Up Survey were analyzed for this study. Standard limits for moderately low birth weight (MLBW) (1500 to 2499 g) and very low birth weight (VLBW) (under 1500 g) were used to categorize children.
      ASTHMA RISK: In this nationally representative, longitudinal sample of 3-year-olds, the prevalence of asthma was 7.1%. Asthma prevalence was 21.9% among VLBW children and 10.9% among MLBW children, compared with 6.7% among children with normal birth weight. Children with VLBW had nearly 3 times the risk of physician-diagnosed asthma compared with those born weighing 2500 g or more. Children in the MLBW category had a smaller but still significant risk. African American race, male sex, and maternal history of smoking were also independently associated with increased risk of early-childhood asthma in the overall population.
      Separate analyses were run on white and African American children. In both populations, male sex was independently associated with asthma, with odds ratios (ORs) of 1.8 for whites and 1.5 for African Americans. Chronic lung disease was also independently associated with asthma in both populations, with ORs of 3.9 for whites and 2.8 for African Americans. Maternal education, maternal age at delivery, and poverty status were not independent contributors to asthma prevalence in both white and African American children.
      DISCUSSION: The effect of birth weight on an individual child's risk for developing asthma was substantial and most pronounced in the lowest birth weight category. Children with VLBW had nearly twice the risk of being diagnosed as having asthma compared with MLBW children and nearly 3 times that of children with normal birth weight.

Search Criteria: Text - Archives of Pediatrics and Adolescent Medicine; V.155; 3/01; p401